Fish oil is oil derived from the tissues of oily fish. Fish oils contain the omega-3 fatty acids Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA), precursors of certain Eicosanoids that are known to reduce inflammation in the body and improve Hypertriglyceridemia. There has been a great deal of controversy in recent years about the role of fish oil in cardiovascular disease, with recent meta-analyses reaching different conclusions about its potential impact. The most promising evidence supports supplementation for prevention of cardiac death.